Disease: Myelodysplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
THPO P40225 thrombopoietin 0.20 0.513 0.692
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
KITLG P21583 KIT ligand 0.85 0.473 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769